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The mixture was then supplemented with Buffer A to bring the final detergent concentration below its CMC (0.008% and 0.01% for DDM and LDAO, respectively) while keeping the final volume to 15 L

Swarbrick A, 2026, Supp Fig S10 from Single-Cell and Spatial Transcriptomic Profiling Reveals Epithelial Functional States and Fibroblast Phenotypes in Hormone TherapyNave Localized Prostate Cancer, Other | 2026 Apostolov E

And the worst part is it creeps up slowly

Short answer: yes, with intelligence

2021 Aug 12;64(15):11183-11194

High levels of MOR are observed in the cortex, thalamus, nucleus accumbens, hippocampus, and amygdala