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Individuals with a history of gastrointestinal surgery or disorders such as Crohns disease, celiac disease, or pernicious anemia may have difficulty absorbing adequate amounts of B12 and folate from their diet, and may require supplementation

Antioxidant Properties The pKa value of GSH (ranging from 8.6 to 8.8 [87,88,89] results in low thiol reactivity in the cellular environment [97]

Table 1 offers a comparative overview of these diagnostic frameworks

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These elements contribute to the restructuring of the ECM, affect the attraction and functioning of immune cells, and interact with other cells in the TME