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Lastly, epithalon plays a significant role in the endocrine system by increasing levels of endogenous hormones that naturally diminish with age, such as melatonin (which helps regulate the sleep cycle), and gonadotropic hormones (FSG, LG, prolactin), which play a role in reproductive functions [8]

In the satellite facility, 16 mice were aged until they reached 90 weeks of age when they underwent cognitive testing

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Luu M, Visekruna A (2019) Short-chain fatty acids: bacterial messengers modulating the immunometabolism of T cells

This remodeling occurs underneath obvious regions of pathology like underneath drusen, but also in regions where cone and rod photoreceptors are still present suggesting implications for altered retinal processing prior to photoreceptor cell death