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Erectile dysfunction and risk of cardiovascular disease: meta-analysis of prospective cohort studies

Disappears upon discontinuation Insomnia if taken late: avoid taking after 4-5 PM, especially combined with caffeine Headaches rare at high doses If you experience digestive effects, split the dose (1 capsule morning + 1 capsule midday) or take during a meal generally improves tolerance

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doi: 10.7554/eLife.78565

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Knowing these risks does not mean you should fear the procedure, it simply helps you approach it with realistic expectations and proper awareness