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FOXO3A regulates peroxiredoxin III expression in human cardiac fibroblasts

doi: 10.1002/mnfr.201300334 67 KumarM.TomarM.PuniaS.Dhakane-LadJ.DhumalS.ChanganS.et al

Earlier GHRP compounds such as GHRP-2 and GHRP-6 stimulate GH release but also elevate other pituitary hormones notably cortisol, prolactin and ACTH

PMCID: PMC2233812

Clinical trials associated with AA-LOX pathway Recent studies showed that a 5-LOX inhibitor, VIA-2291, possessed a protective role against coronary artery disease (NCT00358826) and atherosclerosis (NCT00352417)
Clinically relevant NRF2-modulating agents currently include MMF (approved for relapsing forms of MS), diroximel fumarate (approved for relapsing forms of MS), tegomil fumarate (approved for RRMS by the EMA in 2025), and omaveloxolone (approved for Friedreichs ataxia
