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Since mitochondrial fission is connected with oxidative phosphorylation, metformin-mediated mitochondrial fission increases nutrient oxidation in mitochondria

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doi: 10.1016/00243205(88)904973 142 BarattaMSaleriRMascadriCCoyDHAndresNVTamaniniCet al

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349,350,351,352 Although cargo uploading exogenously is simple and convenient to operate, the integrity of exosomes may be damaged during the loading process, which may affect the effect and require additional purification steps to remove the unloaded drugs

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