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Nature 576 , 459464 (2019)

doi: 10.1016/j.chroma.2020.461864

Afamelanotide mostly hits MC1R and is FDA-approved for a rare skin condition called erythropoietic protoporphyria

V5402 2152 Items Data sheet Features Gluten free Features Dairy free Features Vegetable capsules Features Vegan Features Egg free Features Nuts free Features Fish free Features GMO free Features Soy free Specific References ean13 8436594154027 WARNING: The products displayed here are nutritional supplements as defined by European Directive 2002/46/EC on food supplements

Annu Rev Pharmacol Toxicol (2009) 49:12350

The PLC 2 C-terminal extension has also been shown to influence the equilibrium between membrane-bound and cytosolic populations of this enzyme (Illenberger et al., 2003b)
