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14 - 21 Consequently, as we emphasized, 4 since the original organoprotective/healing intention of stress coping response 22 confronts with unsuccessful realization by the Selyes first mediator in stress response, 25 that integrative mediator that integrates the adaptive bodily response to stress, remains obscured in the highly sophisticated latter Selyes stress concept presentation

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10.3390/molecules24152741 64 MorabitoR.RemiganteA.MarinoA

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The increase in reactive oxygen species and the loss of antioxidant defense mechanisms increase the incidence of SARS-CoV-2 infection and the risk of immune dysfunction and death (65)