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TRT Testosterone replacement therapy can help with underlying biochemical deficiencies leading to decreased libido, says Calvert

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10.1001/archneur.59.10.1541 206 SimaniL.RyanF.HashemifardS.HooshmandiE.MadahiM.SahraeiZ.et al

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Notably, mitochondrial dysfunction induces endoplasmic reticulum (ER) stress, excessive reactive oxygen species (ROS) production, aberrant autophagy, apoptosis, and disrupted calcium ion homeostasis, culminating in inflammatory imbalance via activated signaling cascades [13,14,15,16,17]

The cross-sectional areas (m 2 ) of the cardiomyocytes from vehicle- and METH-treated mice were measured in an analyst-blinded manner on alphanumerically labeled images to calculate the average area using NIH ImageJ software