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These phenotypic differences lie in single amino acid changes that greatly affect the structure and therefore binding affinity of ApoE, with ApoE3 containing Cys-112 and Arg-158, ApoE2 having Cys-112 and Cys-158, and finally ApoE4 with Arg-112 and Arg-158 (Huang and Mahley, 2014)

Xu JH, Lv EZ, Zhao XF, Yu J, Xu SC, Li JM, Li Z, Xue M, Zhang C, Pan J (2022) Enhanced SERS and catalytic performance via piezoelectric and plasmonic coupling effects for organic pollutant molecule degradation
Tomita et al , 2003
This establishes FOXO4-DRI as a genuine inducer of TASC: Targeted Apoptosis of Senescent Cells
GLP1 and cardiovascular outcomes in patients with type 2 diabetes