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DISCUSSION Both naloxone, a morphine antagonist, and gastric pentadecapeptide BPC 157 promptly counteract the morphine-analgesia effect in the hot-plate tested mice

For stroke, a trial of ebselen treatment and stroke showed some promising results of ebselen in improving outcomes [110], however this study has not been replicated and there is no clear association of stroke risk or outcomes with GPx1 polymorphisms [111, 112]

doi: 10.1002/biof.1476 251 SealeL

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