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GPX4-null mice undergo embryonic lethality, whereas conditional GPX4-mutant mice result in ferroptosis, neurodegeneration [112], loss of antiviral immunity [113], infertility, and ischemia-reperfusion injury in the kidney and liver [114]

Headaches: Occasionally reported, particularly during initial use

Anesthesiology 58(4):384-6

"Dual GIP and GLP-1 Receptor Agonism Restores Islet Function and Insulin Sensitivity in Type 2 Diabetes." Cell Metabolism, 2021, 34(7), 1075-1089.

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Furthermore, a broad spectrum of substances may produce ROS exogenously