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Their versatility lies in efficiently carrying both hydrophilic and hydrophobic substances which can be facilitated by easy surface modification and non-immunogenicity, and also achieve active targeting by coupling appropriate ligands onto their surface

In the LPS-induced acute lung injury mouse model, treatment of GHK-Cu also significantly suppressed TNF- and IL-6 expression with a significant decrease of both NF-B p65 and p38 MAPK signaling, suggesting that GHK-Cu is useful for the development of novel anti-inflammatory therapies [22]

doi: 10.1016/j.jaci.2016.06.010

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This makes the overall treatment with semaglutide more comfortable and tolerable, ensuring better adherence and more consistent results for patients