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Such as psoriasis, an inflammatory skin disease, is characterized by erythematous plaques resulting from keratinocyte hyperproliferation (95), although the epigenetic elements of trained immunity in human psoriasis have not been fully defined, studies using imiquimod (IMQ)-induced murine psoriasis models have demonstrated that EpSCs retain innate immune memory by maintaining chromatin accessibility following inflammation

J Am Coll Cardiol 45(8):1295-1301

Progress toward acetate supplementation therapy for Canavan disease: glyceryl triacetate administration increases acetate, but not N-acetylaspartate, levels in brain

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They may also enable non-invasive health monitoring, using skin microbiome data to detect broader health indicators such as immune responses or metabolic conditions and support predictive dermatology by anticipating skin issues and allowing for customized preventative care