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Description
In the G1 phase, ROS-mediated oxidation/phosphorylation of cyclin-dependent kinase 2 (CDK2) promotes its activation, facilitating the G1/S transition
Eisa et al
These bioenergetic improvements were accompanied by upregulation of genes related to mitochondrial function and neuronal repair, suggesting a combination of enhanced mitochondrial function and improved cellular homeostasis
The compound also reduced adipocyte size by 30% and volume by 40%, while cutting lipogenesis by 50-70%
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10.1186/bcr1392 Breast Cancer Res
