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Specialized drugs for conditions like cancer, autoimmune diseases, etc., which often require careful dosing and monitoring

Further investigation revealed that irisin, through SIRT1 regulation, reduced lactate synthesis and apoptosis by inhibiting lactate metabolism-related genes

doi: 10.1096/fj.04-3260com

Its HDAC inhibitory activity directly contributes to the reactivation of silenced tumor suppressor genes and is a key mechanism underlying its remarkable anti-tumor effects in urologic and other cancers, as observed both in vitro and in vivo without significant toxicity (64)

doi: 10.1007/s11886-016-0755-4