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Griffin, W

In contrast to the reversibly hyperoxidized cysteine sulfenylated proteins, irreversibly hyperoxidized sulfonylated cysteine is generally thought to be an impaired dead end product (e.g., inactivated protein) formed through protein aggregation 25

Phosphorylation levels of JAK1, STAT1, and STAT3 were significantly reduced when treated with curcumin, although no such effect was observed when miR-99a was knocked down (Li et al., 2018)

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These systems are also commonly acknowledged as essential in glaucoma [94,95]

The ER oxidoreductases ERdj5 and SEPN1 counteract this accelerated ion flux, and activate SERCA by reducing its oxidation 16,124