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To ask whether other -KG-producing enzymes regulate the YBX1AMPK axis similarly to GDH1, we further knocked down GPT2 and/or GOT2 in Huh7 and H1299 cells and found that GPT2 and GOT2 single or double depletion minimally impacted YBX1 and AMPK expression and intracellular -KG abundance (Supplementary Fig

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References Markle HV, Greenway DC

Carcinogenesis 25(1):8390 Singh A, Sharma N, Ghosh M, Park Y, Jeong D (2017) Emerging importance of dietary phytochemicals in fight against cancer: role in targeting cancer stem cells

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