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Specifically, S203 phosphorylation of PGK1 mediates translocation to the mitochondria, and thus inhibits pyruvate metabolism 34

While exercise independently improved muscle strength, the addition of soy isoflavones (70 mg/day) did not yield significant additive benefits for muscle function or bone density

Patients taking levothyroxine should be particularly attentive to symptoms that might indicate thyroid dysfunction versus medication side effects

PD-L1-targeted microbubbles loaded with docetaxel produce a synergistic effect for the treatment of lung cancer under ultrasound irradiation

For transfection (all volumes per dish), 4 L of Lipofectamine RNAimax (Life Technologies) was combined with 250 L OPTI-MEM (Life Technologies) and separately 30 pmol of siRNA was combined with 250 L of OPTI-MEM

J Biol Chem 249:15721586