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Bartholomew's Hospital Rep

Punicalagin exhibits poor small intestinal bioavailability due to its large molecular weight (1084 Da) and extensive hydrogen bonding capacity (29), which enables it to reach the colon where interaction with gut microbiota occurs

Baxter BA, Parker KD, Nosler MJ, Rao S, Craig R, Seiler C, Ryan EP (2020) Metabolite profile comparisons between ascending and descending colon tissue in healthy adults

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