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In addition to ESCs, the next clinical trial is investigating the safety and efficacy of autologous iNSC-DAP in the treatment of PD in China [123], while a US-based phase 1 interventional study with 7 participants is examining the safety and efficacy of the transplantation of human iPSC-derived dopaminergic progenitors [124]

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PMID 2886936

Powley MW, Sobol Z, Johnson GE et al (2024) N-nitrosamine impurity risk assessment in pharmaceuticals: utilizing in vivo mutation relative potency comparison to establish an acceptable intake for NTTP