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Simultneamente, una mayor disponibilidad de S-adenosilmetionina (SAM) favorece las vas clave dependientes de la metilacin, cruciales para la regulacin epigentica y la expresin gnica relacionada con el metabolismo energtico

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The weight loss effect depends specifically on AMY1R and AMY3R activation, as confirmed by a study in eBioMedicine that showed cagrilintide lowers body weight through these specific receptor subtypes in the brainstem

doi: 10.1016/j.ekir.2022.12.014 130 DhillonS

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