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This pathway branches from glycolysis at the level of Glc-6-P: thus, its alternative designation, the hexose monophosphate shunt

doi: 10.1186/s13008-024-00127-9 45

The following protocol yielded reproducible circular colonies

Among tyrosine kinase inhibitors, imatinib (a PDGFR inhibitor) and erlotinib (an EGFR inhibitor) induce ROS-dependent apoptosis in melanoma and non-small-cell lung cancer cells, respectively, through disruption of mitochondrial membrane potential upon the stimulation of JNK and p38 phosphorylation 88,89 , while vemurafenib (a BRAF inhibitor) increases the production of superoxide anions with the commensurate depolarization of the mitochondrial membranes in melanoma cells 90

10.1146/annurev.pharmtox.45.120403.095857 31 HayesJ

were the first to report abnormalities of Purkinje cells in the cerebella of people with autism