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2014": Rapid tumor regrowth resumed as soon as therapy was discontinued, whereas combination therapy with the HIF1 inhibitor digoxin prevented BCSC enrichment and resulted in tumor eradication (Samanta et al, 2014)

[DOI] [PMC free article] [PubMed] [Google Scholar] 52.Youm Y.-H., Nguyen K.Y., Grant R.W., Goldberg E.L., Bodogai M., Kim D., DAgostino D., Planavsky N., Lupfer C., Kanneganti T.D., et al

However, at times the medications can lead to significant side effects making it not tolerable, or after some time they fail to work

Ferroportin-dependent iron homeostasis protects against oxidative stress-induced nucleus pulposus cell ferroptosis and ameliorates intervertebral disc degeneration in vivo

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