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Due to the intrinsic properties of both signaling cascades, similar sub-toxic concentrations of peroxides, of the order of 100 M extracellular H 2 O 2 , end up fully activating both transcription factors, OxyR and Pap1, even though Tpx1 senses peroxides more than 10 times faster than OxyR (Fig

This bsAb aims to deplete autoreactive B cells while simultaneously modulating T cell activity

PMC 1594586

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Brain-specific endothelial induction of prostaglandin E 2 synthesis enzymes and its temporal relation to fever

In addition to its role in oxidizing macromolecules such as proteins and lipids, H 2 O 2 has also been proposed to function as a signal to induce the expression of genes involved in the senescence process ( Arabidopsis could be induced by ozone (Miller et al., 1999) and the expression of many other SAGs were also induced by ROS ( 2 O 2 treatment in both leaves and roots ( Distinct from the positive role of ROS in senescence, NO can both provoke and impede this process, dependent upon its concentration and subcellular location