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doi: 10.1016/j.trecan.2021.02.004 Summary Keywords metabolic reprogramming, phosphoglycerate dehydrogenase (PHGDH), serine metabolism, serine synthesis pathway (SSP), targeted therapy, tumor immune microenvironment Citation Su P, Yang Y and Zheng H (2026) The serine code of metabolic reprogramming: multidimensional roles of the serine synthesis pathway in tumors and novel breakthroughs for targeted therapy

[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Stowe H.D., Lawler D.F., Kealy R.D

10.1016/j.brainres.2016.08.031 Brain Res

Although the exact mechanisms underlying cysteine and glycine deficiency in type 2 diabetes are not clear, the net result of this deficiency could have a domino effect leading to oxidative stress and tissue damage

[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Grimsrud P.A., Xie H., Griffin T.J., Bernlohr D.A

It can inhibit the aggregation of pathological proteins, mitigate oxidative stress, and suppress neuroinflammation, while enhancing the expression of neurotrophic factors and promoting autophagy, aiding in the clearance of damaged cellular components (Gao et al., 2020