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In another study, oral administration of sertraline was found to cause testicular DNA damage and acute testicular injury in male albino rats, as evidenced by significant degeneration and necrosis of germ cells within the seminiferous tubules, as well as interstitial edema and vascular congestion

Human data are limited

Given the wide variety of symptoms and potential long term effects of untreated B12 deficiency, its important to be aware of the signs and seek medical advice if you suspect youre affected

Cell Immunol 270:5361

As liver function slows (though laboratory tests are usually normal), complete breakdown of metabolites becomes compromised

Supplements are typically out of pocket