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The NLRP3 inflammasome promotes the release of pro-inflammatory cytokines such as IL-18, which activate NK cells and CD4 + T cells, thereby strengthening immune responses and protecting epithelial cells from damage [87, 87]

Other CYP450 enzymes including CYP2B6 and CYP2C9 also play important roles in psychiatric drug metabolism

Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment

346,347 see Figure 27

The development of a new efficacious drug to delay, and hopefully prevent, the onset of AD symptoms must catch up with these efforts

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