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Patients with pernicious anemia have about 3 times the incidence of carcinoma of the stomach as the general population, so appropriate tests for this condition should be carried out when indicated

Please Note: If this panel is ordered by a female, due to ordering restrictions on certain tests, the PSA test will not be included on the requisition and will not be performed

Methylcobalamin is also contraindicated in patients with cobalt hypersensitivity because methylcobalamin contains cobalt

Anemia, characterized by pale or jaundiced skin, is another potential sign, as vitamin deficiency can affect red blood cell production

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Persistently high homocysteine can also risk problems with the cardiovascular system and blood cell formation
