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However, safety depends on several factors: injection site rotation to avoid lipodystrophy, adequate hydration (both agents can increase fluid demand), and monitoring of B vitamin status since semaglutide may affect nutrient absorption slightly during rapid weight loss phases

This essential nutrient also plays a key role in the production of red blood cells, contributing to overall blood and nerve system well-being

[121] Age is also a contributing factor: elderly individuals are often achlorhydric due to reduced parietal cell function in the stomach, increasing their risk of vitamin B 12 deficiency

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Appropriate treatment, within a specified time, is important for restoring motor functions in a person practicing sports or physical activity