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Annu Rev Nutr (2005) 25:21535
When these bacteria are killed off rapidly by antibiotics, they release toxins into the bloodstream, which can cause an acute inflammatory response
APE1 inhibitor APX3330(E3330) could promote the treatment of colorectal cancer tumors by inhibiting the REDOX function of APE1 in combination with 5-FU
Endocrine 49 , 415421 (2014)
J Med Chem 2015, 58:91719178
Ficlatuzumab is currently being tested in combination with cetuximab in a Phase Ib clinical trial of recurrent and metastatic HNSCC (NCT02277197)
