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At week 208, mean weight loss in the semaglutide group analyzed as first on-treatment was 11.7% compared with 1.5% for the placebo group (Fig

Adenosine A2 receptor activation ameliorates mitochondrial oxidative stress upon reperfusion through the posttranslational modification of NDUFV2 subunit of complex I in the heart

Morokuma, K

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No improvement even after increasing to the maximum tolerated dose under medical supervision

described a redox-uptake system mediated by gliotoxin [55]: intracellular gliotoxin can be reduced to dithiol gliotoxin by a cellular reducing agent, thus releasing electrons to cellular O 2 to form O 2 -mediated gliotoxin, which can yield ROS