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To this end, we transfected hESCs with either of two EGFP-based reporter genes, p38 3UTR(wt) or p38 3UTR(mut) (Figure 6A)

The GSSG/GSH redox couple plays a vital role in several enzymatic reactions, including the elimination of peroxides by GSH peroxidases (GPx), in covalent addition of cysteines to proteins by glutaredoxin , and in detoxification of electrophiles by GSH-S-transferase (GST) 585,586,587

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Note that a particular prescription drug for epilepsy control, Depakote (generic: valproic acid), has been found in research to be associated with a significantly increased risk of autism in offspring, when used by mothers during pregnancy

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