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Two of these SNPs, rs2274223 and rs3765524 result in missense mutations in the coding region of PLCE1 gene and cause the amino acid substitutions His1927Arg in the C2 domain and Thr1777Ile in the catalytic domain, respectively [28]

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Plots of ln k (where k is the experimentally determined initial rate) versus 1/ T were calculated from the solvent-free liquid [C-RML][ S 1 ]/pNPPal assay rate data and showed a linear response (Fig

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