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Transthyretin Amyloidosis: Role of oxidative stress and the beneficial implications of antioxidants and nutraceutical supplementation

These pathways include transforming growth factor-beta (TGF), focal adhesion kinases (FAK), phosphatidylinositol 3-kinases (PI3K), extracellular signal-regulated kinase (ERK), Smad2, and Smad7, all of which regulate different molecular processes leading to appropriate and scarless wound healing (Yazarlu et al., 2021)

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doi: 10.1007/s12640-023-00666-z

Additionally, GSH serves as a cysteine reservoir with a proton-donating sulfhydryl function, which allows GSH to act as an antioxidant