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Nonetheless, there is still considerable uncertainty within the therapeutic use of CRISPR/Cas9 for lncRNA targeting in cancer therapy, as offtarget cleavage events can occur despite the system's target specificity [392, 393]

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Cold acclimation alters DNA methylation patterns and confers tolerance to heat and increases growth rate in Brassica rapa

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Opportunities for integration of PDX models into clinical trials, 2016

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