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To accurately identify LTR retrotransposons, LTR-retriever (v2.9.0) 85 software was used to integrate the outputs from LTRharvest (v2.9.0) 86 and LTR_FINDER (v1.07) 87 with default parameters

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The target product ions were determined as m/z 250.10 for SAM (CE 15 V), m/z 136.05 for SAH (CE 20 V) from the precursor ions of [M + H] + ( m / z 399 for SAM, m/z 385 for SAH)

Protective properties of GSB-106 arise from its ability to counteract cell apoptosis via activation of TrkB-dependent pro-survival mechanisms, including inactivation of pro-apoptotic BAD protein and suppression of caspases 9 and 3/7