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Sun, Y., Zhang, Y
It has been established that p21 inhibits cell cycle progression in both G 1 and G 2 through inhibition of several CDKs (Harper et al ., 1993), including CDK2, CDK3, CDK4, CDK6 and CDC2, as well as PCNA, an essential DNA replication factor (Waga et al ., 1994)

Several protective mechanisms are triggered at the cellular level, many of them controlled by the Nrf2 transcription factor, which is normally inhibited by Keap1 [215,216]

Oxidative stress burden decreases

Gives an instant glow
