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Modified versions include an albumin-binding Drug Affinity Complex (DAC) variant, which extends circulating half-life and sustains GH elevation, and a non-DAC variant, which more closely mimics physiological pulsatile secretion patterns

CMS has contracted with the National Committee for Quality Assurance to develop measures that evaluate the quality of care provided by DSNPs (Archibald et al., 2015)
The combination approach was inspired by research showing that amylin and GLP-1 act on different brain regions to reduce appetite

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