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APAP-induced liver injury is associated with glutathione depletion, the formation of APAP protein adducts, the generation of reactive oxygen and nitrogen species and mitochondrial injury

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Method This study is a randomized, double-blind, placebo-controlled three month vitamin/mineral treatment study

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Both sulfur sources increased GSH and Cys content, particularly under high Cd stress, with FeS2 raising GSH and Cys levels by 3.3361.87% and 43.2971.94%, H2SO4 increased 15.6566.43% and 48.0274.58%, respectively (P0.05)