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This review provides a comprehensive analysis of the anatomical considerations in drug absorption, formulation strategies, and technological advancements in intranasal drug delivery devices, emphasising its potential in overcoming traditional drug delivery barriers and unlocking new therapeutic potential for CNS and systemic applications

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Folia Microbiol (Praha) 59:241250

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These microclots are highly resistant to the body's natural breakdown processes because they are bound together by inflammatory proteins, including elevated levels of von Willebrand factor (vWF)