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In diet-induced obese (DIO) mouse models, NNMT inhibition with 5-Amino-1MQ was associated with reduced white adipose tissue mass without affecting food intake, suggesting changes in energy expenditure rather than appetite suppression

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is a Wellcome Trust and Royal Society Sir Henry Dale fellow (104194/Z/14/Z)

The GLP1 receptor antagonist drug semaglutide (Ozempic/Wegovy) is a synthetic peptide

Replacement supports response to prednisolone and dietary therapy

Biochemical and biophysical research communications, 1973, 54(2): 562- 566