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A.CaseyA.McCoyK.et al

Antagonism of the Prostaglandin D2 Receptor 1 Suppresses Nicotinic Acid-Induced Vasodilation in Mice and Humans

Modern day therapeutics that are recombinant DNA based have minimized the issue of heterogeneity, however aggregates are still present to some extent in all drug formulations and need to be studied further
Moreover, all the above abnormalities are rapidly corrected when euglycemia is restored, which makes the phenomenon of hyperglycemic memory conceptually difficult to explain

10.1126/science.aba9102
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