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Although this competitive phenomenon has not yet been observed in the brain, it may be a significant reason for the poor efficacy and side effects of many therapeutic approaches, warranting further investigation

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Norwitz NG, Hu MT, Clarke K

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Cells were washed and incubated with DNase-free RNAse A (100 g/mL

Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy