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Clin Transl Sci

Indeed, diabetic rat models confirmed that in the liver, the induction of TNF results in increased levels of NF-kB and JNK signaling, characterized by further induction of inducible nitric oxide synthase (iNOS) and consequent increase in nitric oxide production, as well as increased apoptosis rates [71]
doi: 10.1161/01.ATV.0000214960.85469.68 142 MukheefMAAliRAAlheideryHHA
Mutagenesis by metal-induced oxygen radicals

On the other hand, NAC serves as a precursor to glutathione

[DOI] [PMC free article] [PubMed] [Google Scholar] Almahdy, O
