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doi: 10.1007/s00406-023-01734-3

[32] It has also been shown to improve type 2 diabetes markers, such as several lipid parameters, as well as lower oxidative stress

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In summary, androgens/AR signaling alleviates mitochondrial oxidative stress by regulating the expression levels of mitochondrial respiratory chain-related enzymes such as Cox1/2 and CytB, decreasing the levels of peroxisomes (e.g., H 2 O 2 and MDA), increasing the antioxidant levels (e.g., SOD2 and GPX1) and enhances OXPHOS capacity through regulating MPC

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