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Firstly, considering the high tumor heterogeneity, various tumors or different regions within the same tumor can exhibit distinct metabolic profiles (Hensley et al., 2016)

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A., Graveley, B

Journal of Pharmacology and Experimental Therapeutics, 340(3), 476-485

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DRD2 induces dimerization of PKM2 to bind with and activate Nrf2 Transcription factor binding to gene promoters requires assistance from coactivators 39
