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Most roseoflavin-resistant strains studied until now carry mutations in the regulatory region upstream of the rib operon (more specifically, in the aptamer of the riboswitch), disrupting the negative feedback mechanism, resulting in significantly higher expression 184,185
70 Collectively, autophagy activation is likely to play a protective role in AIH
doi: 10.1016/j.actbio.2021.06.016
four doses in total) after two cycles of remission induction
-Mangostin protects against drug-induced acute liver injury by mitigating oxidative stress and suppressing inflammation
On behalf of the SODIUM-HF investigators
