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Elevated glutathione levels had a significant negative effect on survival in patients with colorectal cancer, whether based on the mean ( P =0.02) or median ( P =0.04) normal tissue levels

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Aging Cell (2007) 6(3):32736

The endocannabinoid system and the brain

Furthermore, much of the current mechanistic understanding is derived from animal models and isolated compounds, which may not accurately reflect the synergistic effects of a whole-food matrix or the long-term physiological complexities of human metabolic dysfunction

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