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Pretreatment with L-carnitine also attenuated superoxide production and HIF1 expression after OGD, and decreased apoptosis in neurons during reperfusion [54]

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Furthermore, studies in vitro have shown that it inhibits the activity of the metalloproteinases MMP-1 and MMP-2, enzymes involved in the breakdown of the dermal matrix

[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Chiechio S., Zammataro M., Morales M.E., Busceti C.L., Drago F., Gereau R.W., 4th, Copani A., Nicoletti F

L-carnitine modulates cognitive impairment induced by doxorubicin and cyclophosphamide in rats